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The consistently reported poor diagnosis and treatment experience encountered in UK Primary Care by people with a diagnosis, or symptomatic of, Pernicious Anaemia in the UK is well documented and reported on in research carried out and published by the Pernicious Anaemia Society

Its Phase 3 weight-loss figures (in the low-to-mid 20% range) and its late-2025 FDA filing belong to the combination product, not to standalone cagrilintide, which remains at the Phase 2 stage with a peer-reviewed monotherapy result of about 10.8% at 26 weeks

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Both peptides have favorable safety profiles in available research, but long-term data remain limited